Significant shareholders:

Shareholder/Beneficial OwnerShares% ISC
Lombard Odier Investment Managers143,680,42914.79
Canaccord Genuity Wealth Management92,591,7489.53
T Rowe Price Global Investments77,842,8028.02
Artisan Partners74,179,9497.64
Hargreaves Lansdown, stockbrokers71,476,5727.36
Mr Richard Griffiths60,891,4416.27
Interactive Investor59,085,7196.08
Dr Andrew Nelson*38,835,5144.00
M&G Investments38,159,6633.93

as at 30 April 2025

Quoted: AIM (London Stock Exchange)

Other Exchanges / Trading Platforms: The Company is not listed on any other exchanges or trading platforms.

Number of securities in issue: 971,198,059 Ordinary shares.

Shares not in public hands: Insofar as the Company is aware, the percentage of securities that is not in public hands is 15.0%, these being held by directors, their families and significant shareholders.

Own shares held in treasury: The Company holds 4,115 Ordinary Shares in treasury.

Details on any restrictions on the transfer of securities: There are no restrictions on the transfer of securities.

Applicable code(s): The Company is subject to the UK City Code on Takeovers and Mergers. The Code is administered by The Panel and Takeovers in Mergers.

* Per the Company’s RNS announcement of 11 May 2020, 12,121,711 Ordinary Shares of Dr Nelson’s total beneficial interest are subject to a Sale and Repurchase Agreement with Equities First Holdings.